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1.
Radiol Case Rep ; 16(8): 2072-2076, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: covidwho-2251858

RESUMEN

The case of 21-year-old man with an asthma history from childhood presenting severe respiratory distress associated with a right lower thoracic pain has been studied. The non-contrast Computed Tomography (CT)-chest scan showed a basal ground-glass opacity (GGO) of the right lung leading to suspicion of COVID-19 pneumonia. However, the molecular Reverse transcription polymerase chain reaction test and blood serology were negative while laboratory analyses revealed high levels of D-dimers (D-D). In addition, 2 repeated COVID-19 tests were negative. A thoracic CT angiography was disclosed due to the persistence of pain at the lower right thoracic side and hemoptysis that shows a bilateral distal pulmonary embolism with a right-sided basal subsegmental ischemia. We discuss a fortuitous discovery of pulmonary embolism associated with peripheral basal ground-glass opacities similar to radiological manifestations of SARS-CoV-2 pneumonia.

2.
Expert Rev Mol Diagn ; 21(2): 141-160, 2021 02.
Artículo en Inglés | MEDLINE | ID: covidwho-1087610

RESUMEN

INTRODUCTION: SARS-Cov-2 first appeared in Wuhan, China, in December 2019 and spread all over the world soon after that. Given the infectious nature ofSARS-CoV-2, fast and accurate diagnosis tools are important to detect the virus. In this review, we discuss the different diagnostic tests that are currently being implemented in laboratories and provide a description of various COVID-19 kits. AREAS COVERED: We summarize molecular techniques that target the viral load, serological methods used for SARS-CoV-2 specific antibodies detection as well as newly developed faster assays for the detection of SARS-COV 2 in various biological samples. EXPERT OPINION: In the light of the widespread pandemic, the massive diagnosis of COVID-19, using various detection techniques, appears to be the most effective strategy for monitoring and containing its propagation.


Asunto(s)
Prueba de Ácido Nucleico para COVID-19/métodos , Prueba de Ácido Nucleico para COVID-19/tendencias , Prueba Serológica para COVID-19/métodos , Prueba Serológica para COVID-19/tendencias , COVID-19/diagnóstico , Anticuerpos Antivirales/inmunología , Técnicas Biosensibles , Sistemas CRISPR-Cas , Técnicas de Laboratorio Clínico , Humanos , Inmunoensayo , Inmunoglobulina G/inmunología , Inmunoglobulina M/inmunología , Laboratorios , Radiografía Torácica , Juego de Reactivos para Diagnóstico , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Tomografía Computarizada por Rayos X
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